IRDye® 800CW PEG Fluorescent Contrast Agent 15nmol

IRDye 800CW PEG Contrast Agent (25-60 kDa) is a non-specific imaging agent intended to exploit enhanced permeability and retention (EPR) in tumor biology.

EPR is a common characteristic of tumor vasculature. The vascular endothelium in the tumor microenvironment is often discontinuous, allowing molecules to diffuse into the surrounding tumor tissue.^{1, 2} In addition to EPR, the lymphatic drainage for these regions is poor.³ Hence, larger molecules tend to accumulate.